Bextra
What is Bextra and what is it used for?
Bextra is the brand name for valdecoxib, a COX-2 selective non-steroidal anti-inflammatory drug (NSAID) which is indicated for the treatment of osteoarthritis, rheumatoid arthritis and dysmenorrhea (menstrual pain).
Who should not take Bextra?
You
should not take Bextra if you are allergic to Bextra or to any of the
ingredients in Bextra or have asthma, hives or allergic reactions after
taking aspirin or other NSAIDs or COX-2 inhibitors.
Some examples of NSAIDs are:
- Ibuprofen (Motrin, Advil),
- Naproxen (Naprosyn, Aleve),
- Diclofenac (Voltaren, Cataflam),
- Nabumetone (Relafen)
- Ketoprofen (Orudis)
- Celecoxib (Celebrex)
- Rofecoxib (Vioxx)
Special Warnings with Bextra:
Bextra and all NSAID medications can cause stomach ulcers
that bleed. The chance of this serious problem increases the
longer you take Bextra, but it can also happen suddenly.
Stop taking Bextra and call your doctor right away if you get:
- A burning stomach pain
- Black bowel movements that look like tar
- Vomit that looks like blood or coffee grounds
General Precautions with Bextra:
Bextra and other NSAID medications can cause serious problems
such as liver damage. Some of the warning signs of liver damage
are nausea, vomiting, tiredness, loss of appetite, itching,
yellow coloring of skin or eyes, "flu-like" symptoms
and dark urine. If this happens, stop taking Bextra and call
your doctor right away.
Bextra can cause fluid retention (holding of water in your body). Fluid retention can be a serious problem if you have high blood pressure or heart failure.
Do not use Bextra if you have asthma and are allergic to aspirin. If an aspirin-sensitive asthmatic takes aspirin it can cause severe narrowing of the airway (bronchospasm), and even death. The same reactions to aspirin and other NSAID medicines happened in aspirin-sensitive patients.
What should I tell my health care provider?
Tell your health care provider if you:
- Have heart problems or high blood pressure
- Have liver or kidney problems
- Have or had stomach ulcers or stomach bleeding
- Have asthma
- Are allergic to aspirin or other NSAID medicines
- Are pregnant or planning to become pregnant
- Are breast-feeding
Tell your health care provider about all the medicines that you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements. Your health care provider may have to adjust your dose or watch you more closely if you take the following medications:
- Certain blood pressure medicines called ACE inhibitors
- Furosemide (Lasix)
- Fluconazole or ketoconazole
- Lithium
- Warfarin (coumadin)
- Aspirin
What are some possible side effects of Bextra?
Side effects can include:
- Indigestion
- Nausea
- Stomach pain
- Upper respiratory tract infection
- Diarrhea
- Headache
This is NOT a complete list of side effects reported with Bextra. Additional Bextra Side Effects.

